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Protein Misfolding

Wednesday, June 30, 2021 - 3:00pm to 4:00pm


Marina Ramirez-Alvarado, Ph.D.
Professor, Biochemistry and Molecular Biology
Mayo Clinic


Marina Ramirez-Alvarado, Ph.D., studies misfolding and amyloid formation in light chain amyloidosis. The overall goal of her research laboratory is to understand the molecular basis of this disease to find ways to ameliorate the organ damage it causes and find new therapeutic strategies to improve organ function and quality of life for patients, ultimately increasing overall survival.

The amyloidoses are a group of protein misfolding diseases characterized by the accumulation of insoluble amyloid fibrils that lead to cell death and tissue degeneration. There are 36 different human amyloid diseases. Understanding the molecular determinants that drive protein misfolding and aggregation will help Dr. Ramirez-Alvarado and her colleagues understand these diseases and guide them to design therapeutic strategies to overcome the effects of amyloidogenesis.

The page was last updated on Thursday, December 24, 2020 - 11:07am