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NIH Office of Intramural Research

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  • About OIR
    • OIR Leadership & Staff
      • Nina F. Schor, M.D., Ph.D.
      • Richard G. Wyatt, M.D.
      • Janice Lee, D.D.S., M.D., M.S.
      • Andy Baxevanis, Ph.D.
      • Charles R. Dearolf, Ph.D.
      • Nadine Fonrose, M.A.
      • Arlyn García-Pérez, Ph.D.
      • Carl Hashimoto, Ph.D.
      • Roland A. Owens, Ph.D.
      • Kathryn M. Partin, Ph.D.
      • Rena Rodriguez, B.S.
      • Dierdre S. Andrews
      • Diana Gomez
      • Chanee' M. Jackson
      • Margaret McBurney, M.B.A.
      • Karen Nemes
      • Lisa L. Coronado, M.B.A.
      • Dan Fogarty, M.A., FACHE
      • Bonny Harbinger, Ph.D., J.D.
      • David B. Resnik, J.D., Ph.D.
      • Mark L. Rohrbaugh, Ph.D., J.D.
      • Parker Ruhl, M.D., M.H.S.
    • Diversity & Inclusion
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      • IRP Repository for COVID-19 Samples
      • Rapid Review of Human Subjects Research Related to the SARS-CoV-2 Pandemic
      • Donating Personal Protective Equipment (PPE) and COVID-19 Testing Supplies
      • Exceptional Use of IC Funds for Per Diem Quarantine for Non-FTE Trainees (VF/IRTA/CRTA)
      • Student IRTA/CRTA and Student Special Volunteers
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    • Board of Scientific Directors
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        • Official List of Approved Intramural Professional Designations (IPDs)
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      • Policies and Recruitment Processes
        • 5-Year / 8-Year Duration Rule
        • Departing Staff Request to Remove Copies of NIH Records
        • Example IC Check Sheets / Checklists
        • Exceptional Extensions of IRTA and Visiting Fellowships to a 6th Year
        • Fair Review Principles for Nominations of Staff Scientists for Associate Scientist and Senior Associate Scientist Titles
        • Guide for Avoiding Undue Foreign Interference with IRP Research
        • Guidelines for Parental/Family Excused Absence for IRTAs, CRTAs, and Visiting Fellows
        • Keep The Thread Policy
        • Mandated Training for Scientific Staff Working in NIH Facilities
        • Policy for Reassignment or Early Termination of Awards to Postbaccalaureate Fellows
        • Policy for Reassignment or Early Termination of Awards to Postdoctoral Fellows
        • Policy for Reassignment or Early Termination of Awards to Predoctoral Fellows
        • Policy for Use of Contract Workers to Support Scientific Functions in the IRP
        • Policy on Use of English for Official Scientific Communication in NIH Laboratories and Branches
        • Postdoctoral Fellows (IRTA/CRTA/VF) Temporary Exceptional Extensions Policy
        • Roles of Lab and Branch Chiefs (or Equivalent)
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        • Working with Displaced Title 42 Staff Scientists/Clinicians
      • IRP Demographics
        • Intramural Research Program Personnel Demographics (End FY22)
        • Foreign Nationals in the Intramural Research Program (End FY22)
        • Intramural Research Program Personnel Demographics (End FY21)
        • Foreign Nationals in the Intramural Research Program (End FY21)
        • Intramural Research Program Personnel Demographics (End FY20)
        • Foreign Nationals in the Intramural Research Program (End FY20)
        • Intramural Research Program Personnel Demographics (End FY19)
        • Foreign Nationals in the Intramural Research Program (End FY19)
        • Intramural Research Program Personnel Demographics (End FY18)
        • Foreign Nationals in the Intramural Research Program (End FY18)
        • Intramural Research Program Personnel Demographics (End FY17)
        • Foreign Nationals in the Intramural Research Program (End FY17)
        • Intramural Research Program Personnel Demographics (End FY16)
        • Foreign Nationals in the Intramural Research Program (End FY16)
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    • Tenure in the NIH Intramural Research Program
      • Tenure-Track Overview
      • Search & Selection
        • Search Process for Senior Investigators, Tenure-Track Investigators, Senior Clinicians and Senior Scientists
        • Role of Search Committee Members
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      • Statement About PI Involvement in Diversity, Equity, Inclusion, and Accessibility
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    • Awards, Fellowships, & Grant Opportunities
      • The Director’s Challenge Innovation Award Program
        • 2020 Director’s Challenge Awards
        • 2022 Director’s Challenge Awards
      • Early Career (Bridge) Awards Open to IRP Scientists
      • Eligibility of Intramural Investigators for NIH Common Fund Awards
      • K99/R00 Grant Award Information
        • Application Approval Process and Additional Information
        • K99/R00 Environment and Institutional Commitment Statement
        • Update from Scientific Directors
      • NIAID Support of Intramural Biodefense Research from ICs Other Than NIAID
    • Ethical Conduct
      • Research Misconduct
        • Anonymous Reporting of Research Misconduct Concerns
        • Taraswi Banerjee, Ph.D.
        • Alfredo R Sancho, Ph.D., M.P.H.
      • Guidelines on Conduct of Research
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          • Intramural / Extramural Collaborations
            • NIH Staff Involvement on Extramural Awards - Cooperative Agreements
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        • NIH Guidelines
          • Guide for Human Biospecimen Storage and Tracking
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      • Special Research Considerations
        • Dual-Use Research
        • Human Stem Cell Use
          • Human Embryonic Stem Cell (hESCs) Use
          • Induced Pluripotent Stem Cells (iPSCs) Use
          • Human Embryo Research and Cloning Prohibitions
        • Policies & Procedures for Human Fetal Tissue Research
          • Policies on the Acquisition and Use of HFT
          • Procedures for Obtaining HFT
      • Responsible Conduct of Research Training
        • Instruction in Responsible Conduct of Research - Postdoc IRTA, CRTA, VF, Research Associates
          • Reproducibility Training
          • Introduction to “My Laboratory”
        • Instruction in Responsible Conduct of Research - Postbacs and GPP Students
        • Resources for Training Directors
        • Annual Review of Ethics (Case Studies)
          • Research Cases for Use by the NIH Community
            • 2021 Ethics Case Facilitator Training
        • Processes for Authorship Dispute Resolution
      • Government Ethics
        • Guidelines for Non-FTEs (Trainees) for NIH-Related Activities, Outside Activities, and Awards
      • Bioethics
    • Mentoring & Training
      • Guide to Training and Mentoring
      • Guidelines for Mentors at NIH
      • Guidelines for Trainees at NIH
      • Guidelines for Annual Progress Review of Trainees
      • Scientific Director Policy Updates for Mentors and Trainees
      • Goals for Enhanced Mentoring in the IRP
      • FelCom Mentoring Committee
      • The DDIR Implementation Plan in Response to the FelCom Subcommittee Report on Mentoring
      • Mentoring Cases for Discussions
    • Submitting Research Publications
      • PubMed Central (PMC) Deposition Requirements
      • Intramural Directions for Submitting to PubMed Central via NIHMS
      • NIH Publishing Agreement Forms
        • Procedures for Non-Peer-Reviewed Publications
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  • IRP Website
    • A premier environment where creative scientists conduct fundamental research for the betterment of human health – we are the IRP
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    • The NIH Research Festival is the showcase for intramural research
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    • A publication for and about the NIH intramural research community
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Andy Baxevanis, Ph.D.

Director of Computational Biology, OIR

B.S., Cornell University, 1984

Ph.D., The Johns Hopkins University, 1991

Building 50, Room 5222
50 South Drive
Bethesda, MD 20892

301-496-8570

andy@mail.nih.gov

Dr. Baxevanis is the Director of Computational Biology for the National Institutes of Health’s Intramural Research Program. In this role, he has responsibility for addressing a wide range of bioinformatic and computational issues of importance to the NIH Intramural Research Program. He is currently leading a number of strategic planning initiatives aimed at improving the IRP’s computational infrastructure and high-performance computing capabilities, in an effort to meet the ever-growing scientific computing needs of all IRP investigators; this has included a major expansion of the IRP’s high-performance computing environment, creating and providing IRP researchers access to one of the top-ranked supercomputers worldwide. Dr. Baxevanis served as the Deputy Scientific Director of the National Human Genome Research Institute (NHGRI) from 1998 to 2011 before assuming his current position.

Dr. Baxevanis is also a Senior Scientist leading the NHGRI’s Computational Genomics Unit. His research program focuses on the use of phylogenetic and comparative genomic techniques to study developmental proteins that play a fundamental role in the specification of body plan, pattern formation, and cell fate determination during metazoan development. His group uses a variety of computational approaches to understand the evolution and function of these proteins and their ultimate role in human disease. Building upon prior work on the origin and early evolution of Hox genes, his research group’s focus has turned to analyzing the genomes of early branching metazoan phyla to better-understand the relationship between genomic and morphological complexity, as well as the evolution of novel cell types. Using a variety of next-generation sequencing and bioinformatics techniques, his group recently completed the sequencing, annotation, and analysis of the genome of the ctenophore Mnemiopsis leidyi. This work has brought resolution to the question of the phylogenetic position of the ctenophores, placing them as the sister group to all other animals, also demonstrating that the genetic blueprint for complex, multicellular organisms was present even in our distant animal relatives. He is also one of the lead investigators of the Multiplex Initiative, a large-scale, multi-center clinical and behavioral study aimed at exploring why patients elect (or decline) genetic susceptibility tests, how they interpret test information and results, and how they will ultimately use this knowledge in future health care decisions.

Dr. Baxevanis is co-author of the textbook Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins, whose fourth edition will be published shortly. He also currently serves on a number of editorial and academic scientific advisory boards. His involvement in educational activities have included teaching bioinformatics at The Johns Hopkins University, serving as an adjunct faculty member at Boston University, and lecturing in numerous courses, such as NHGRI’s Current Topics in Genome Analysis series. Until recently, he also served as the Co-Director of the Boston University/NIH Graduate Partnerships Program in Bioinformatics.

Dr. Baxevanis’ accomplishments have been recognized by the Bodossaki Foundation, who awarded him their 2000 Academic Prize in Medicine and Biology; this award is Greece’s highest honor for young academics and scientists of Greek heritage throughout the world. In 2007, Dr. Baxevanis was awarded the IEEE Computer Society’s Outstanding Achievement Award for his outstanding contributions to the field of bioinformatics. In 2014, he was elected to membership in the Johns Hopkins Society of Scholars, which recognizes alumni who have achieved marked distinction in their field of study. Dr. Baxevanis was the recipient of the NIH’s Ruth L. Kirschstein Mentoring Award in 2015, in recognition of his commitment to scientific training, education, and mentoring. In 2016, Dr. Baxevanis was elected as a Senior Member of the International Society for Computational Biology for his sustained contributions to the field and, in 2018, he was elected as a Fellow of the American Association for the Advancement of Science for his distinguished contributions to the field of comparative genomics.

This page was last updated on Wednesday, May 18, 2022

Main navigation

  • OIR Leadership & Staff
    • Nina F. Schor, M.D., Ph.D.
    • Richard G. Wyatt, M.D.
    • Janice Lee, D.D.S., M.D., M.S.
    • Andy Baxevanis, Ph.D.
    • Charles R. Dearolf, Ph.D.
    • Nadine Fonrose, M.A.
    • Arlyn García-Pérez, Ph.D.
    • Carl Hashimoto, Ph.D.
    • Roland A. Owens, Ph.D.
    • Kathryn M. Partin, Ph.D.
    • Rena Rodriguez, B.S.
    • Dierdre S. Andrews
    • Diana Gomez
    • Chanee' M. Jackson
    • Margaret McBurney, M.B.A.
    • Karen Nemes
    • Lisa L. Coronado, M.B.A.
    • Dan Fogarty, M.A., FACHE
    • Bonny Harbinger, Ph.D., J.D.
    • David B. Resnik, J.D., Ph.D.
    • Mark L. Rohrbaugh, Ph.D., J.D.
    • Parker Ruhl, M.D., M.H.S.
  • Diversity & Inclusion
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Main navigation

  • About OIR
    • OIR Leadership & Staff
    • Diversity & Inclusion
    • Intramural Targeted Anti-COVID-19 (ITAC) Awards
    • DDIR Innovation Awards
    • Long-Term IRP Planning
    • OIR Offices
  • Sourcebook
    • Intramural COVID-19 Guidance and Resources
    • Board of Scientific Directors
    • Committees Advisory to the DDIR
    • Processes for Reviewing NIH Intramural Science
    • Intramural Program Oversight
    • Intramural Administrative Management Council
    • Personnel
    • Tenure in the NIH Intramural Research Program
    • Awards, Fellowships, & Grant Opportunities
    • Ethical Conduct
    • Mentoring & Training
    • Submitting Research Publications
    • Intramural Research Communications & Resources
  • WALS
    • About WALS
    • Current Lecture Season
    • Past Lecture Seasons & Speakers
    • Named & Honorific Lectures
    • WALS Lunch Request
    • Continuing Medical Education Credits
  • SIGs
    • SIGs by Name
    • SIGs by Scientific Focus Area
  • IRP Website
    • A premier environment where creative scientists conduct fundamental research for the betterment of human health – we are the IRP
    • Visit Website
  • NIH Research Festival
    • The NIH Research Festival is the showcase for intramural research
    • Visit Website
  • The NIH Catalyst
    • A publication for and about the NIH intramural research community
    • Visit Website
  • NIDB
    • The NIH Intramural Database collects and disseminates information about research being performed in the Intramural Programs
    • Visit Website
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