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      • Nina F. Schor, M.D., Ph.D.
      • Roland A. Owens, Ph.D.
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      • Andy Baxevanis, Ph.D.
      • Charles R. Dearolf, Ph.D.
      • Nadine Fonrose, M.A.
      • Arlyn García-Pérez, Ph.D.
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    • Processes for Reviewing NIH Intramural Science
      • Boards of Scientific Counselors (BSC)
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        • 2023 NIH Data Management and Sharing Policy
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          • Frequently Asked Questions: NIH Clinical Trial Definition
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        • 5-Year / 8-Year Duration Rule
        • Addendum to On-Site Research Collaborators (RC) Policies: On-Site RC Conducting Human Subjects Research at NIH
        • Clarification on Searches for Scientific Director and Clinical Director
        • Departing Staff Request to Remove Copies of NIH Records
        • Extension Exceptions for Non-FTE Trainees for COVID-19
        • Fair Review Principles for Nominations of Staff Scientists for Associate Scientist and Senior Associate Scientist Titles
        • Guide for Avoiding Undue Foreign Interference with IRP Research
        • Guidelines for Parental/Family Excused Absence for IRTAs, CRTAs, and Visiting Fellows
        • Mandated Training for Scientific Staff Working in NIH Facilities
        • Policy for a Letter of Agreement for Staff Scientists
        • Policy for Reassignment or Early Termination of Awards to Postbaccalaureate Fellows
        • Policy for Reassignment or Early Termination of Awards to Postdoctoral Fellows
        • Policy for Reassignment or Early Termination of Awards to Predoctoral Fellows
        • Policy for Use of Contract Workers to Support Scientific Functions in the IRP
        • Policy on Use of English for Official Scientific Communication in NIH Laboratories and Branches
        • Postdoctoral Fellows (IRTA/CRTA/VF) Temporary Exceptional Extensions Policy
        • Roles of Lab and Branch Chiefs (or Equivalent)
        • Telework Policies for IRTA/CRTA and Visiting Fellows
        • Working with Displaced Title 42 Staff Scientists/Clinicians
      • Quality-of-Life Features
      • Sabbaticals
        • NIAAA Sabbatical Program
        • NEI Sabbatical Program
        • NICHD Sabbatical Program
        • PHS Foreign Work / Study Program Policy
      • Opportunities for Short Assignments / Details at the NIH
    • Tenure in the NIH Intramural Research Program
      • Tenure-Track Overview
      • Search & Selection
        • Search Process for Senior Investigators, Tenure-Track Investigators, Senior Clinicians and Senior Scientists
      • Additional Tenure-Track Policies
      • Resources
      • Policy on IC Tenure Review Committees
      • Tenure Overview
      • Search & Selection
      • Criteria for Tenure at the NIH
      • De-Tenuring Process
    • Awards, Fellowships, & Grant Opportunities
      • The Director’s Challenge Innovation Award Program
        • 2020 Director’s Challenge Awards
        • 2022 Director’s Challenge Awards
        • 2024 Director’s Challenge Awards
      • Early Career (Bridge) Awards Open to IRP Scientists
      • Eligibility of Intramural Investigators for NIH Common Fund Awards
      • K99/R00 Grant Award Information
        • Application Approval Process and Additional Information
        • K99/R00 Environment and Institutional Commitment Statement
        • Update from Scientific Directors
      • NIAID Support of Intramural Biodefense Research from ICs Other Than NIAID
    • Ethical Conduct
      • Research Misconduct
        • Anonymous Reporting of Research Misconduct Concerns
        • Taraswi Banerjee, Ph.D.
        • Alfredo R Sancho, Ph.D., M.P.H.
      • Guidelines on Conduct of Research
      • Research Ethics
        • NIH Policies
          • Intramural / Extramural Collaborations
            • NIH Staff Involvement on Extramural Awards - Cooperative Agreements
              • Opportunities for Collaborative Research at the Clinical Center (U01)
              • NIH Bench-to-Bedside Program
            • Activities with Outside Organizations
          • NIH Human Biospecimen Program
            • Frequently Asked Questions
            • List of Biospecimen Liaisons
          • Investigation of Allegations of Research Misconduct
        • NIH Guidelines
      • Authorship Guidelines and Resources
        • Authorship Resources
        • NIH IRP Authorship Conflict Resolution Process
      • Special Research Considerations
        • Dual-Use Research
        • Policy on the Ordering or Provision of Synthetic Nucleic Acids in the IRP
        • Human Stem Cell Use
          • Human Embryonic Stem Cell (hESCs) Use
          • Induced Pluripotent Stem Cells (iPSCs) Use
          • Human Embryo Research and Cloning Prohibitions
        • Policies & Procedures for Human Fetal Tissue Research
      • Responsible Conduct of Research Training
        • Instruction in Responsible Conduct of Research - Postdoc IRTA, CRTA, VF, Research Associates
          • Reproducibility Training
          • Introduction to “My Laboratory”
        • Instruction in Responsible Conduct of Research - Postbacs and GPP Students
        • Resources for Training Directors
        • Annual Review of Ethics (Case Studies)
          • Research Cases for Use by the NIH Community
            • 2021 Ethics Case Facilitator Training
      • Government Ethics
        • Guidelines for Non-FTEs (Trainees) for NIH-Related Activities, Outside Activities, and Awards
      • Bioethics
    • Mentoring & Training
      • Guide to Training and Mentoring
      • Guidelines for Mentors at NIH
      • Guidelines for Trainees at NIH
      • Guidelines for Annual Progress Review of Trainees
      • Scientific Director Policy Updates for Mentors and Trainees
      • Goals for Enhanced Mentoring in the IRP
      • FelCom Mentoring Committee
      • Mentoring Cases for Discussions
    • Submitting Research Publications
      • PubMed Central (PMC) Deposition Requirements
      • Intramural Directions for Submitting to PubMed Central via NIHMS
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        • Procedures for Non-Peer-Reviewed Publications
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    • A premier environment where creative scientists conduct fundamental research for the betterment of human health – we are the IRP
    • Visit Website
  • The NIH Catalyst
    • A publication for and about the NIH intramural research community
    • Visit Website
  • NIDB
    • The NIH Intramural Database collects and disseminates information about research being performed in the Intramural Programs
    • Visit Website

Independent Research Scholar Program

Program Overview

  • The purpose of this program is to support highly accomplished early career fellows to establish an independent research program and learn mentorship and research group management. The expectation is that the participants will be competitive for Investigator (tenure-track) positions in the IRP and outside after succeeding in this position.
  • Scholars will be independent, non-tenure track Principal Investigators. They will be scientifically independent of their previous mentor. They will be given their own independent resources and CAN. They will be invited to participate in faculty meetings and other Institute/Center (IC) activities along with tenure-track and tenured investigators.
  • Eligible candidates include current NIH FTE research fellows and non-FTE postdoctoral fellows, as well as candidates from outside the NIH. Scholars must have no more than 4 years postdoctoral research in total, and if an internal NIH candidate must also have less than 3 years postdoctoral research in the NIH IRP, as of January 1, 2024. Graduate students currently completing their doctoral degrees may apply. However, it is a Federal government requirement that they must have received their doctoral diploma before they can be hired as an IRS investigator, because these are FTE positions.
  • A postdoctoral fellow whose current mentor is an NIH tenure-track investigator but otherwise meets the eligibility criteria may apply. However, their application is discouraged because the program may not best serve their research and career success, compared to the traditionally successful model where a postdoctoral fellow works within the research program and under the direct supervision of the mentor. There should be a discussion with the Scientific Director about whether participation in the program is in the best interests of such a postdoctoral fellow as well as their mentor.
  • Applicants with a Ph.D., M.D., or other biomedical doctoral degree and with relevant research experience, are eligible for acceptance into the program. The candidates must be US citizens or US permanent residents (“green card“). The position is designed for a three-year period. Ideally, the participants should apply for tenure-track investigator positions, including the NIH Stadtman Investigator search, no later than during their third year. The IRS position may be extended, upon approval of OIR, for a 4th year and no more than a 5th year, but only to allow for the scholar to finalize starting on a tenure-track position here or outside. The extensions must be within the IRP 5yr/8yr rule. IRS investigators remain eligible to apply for a NIH K99/R00 Pathway to Independence Award if they meet the other eligibility requirements of that program.
  • The individuals selected for this program will be hired under the Research Fellow Intramural Professional Designation (IPD), an FTE under T42(g) (time-limited appointment) so that they can manage resources, including trainees. This position is currently exempt from review by the Hiring Controls Committee, but must fall within the Congressional Justification (CJ) ceiling for the IC and be reported on OHR data calls for FTEs.
  • Independent resources allocated to participants - 2 postbaccs or other time-limited technical staff positions (term/temp FTE technician, post-baccalaureate fellows, temporary contract worker, displaced technical staff) and supplies.
  • Estimated budget for the Scholar's first year (See sample Budget Plan): ICs may request from OIR up to $100,000 in one-time startup funds. The IC provides the FTE position as Research Fellow for the duration of the appointment. DDIR/OIR approval of the IRS appointment is required.
  • Participants, in consultation with their mentors, will design a research proposal and career development plan with milestones to be achieved during their time in this position. Each participant must have mentors in addition to their lab mentor. The mentors’ involvement is envisioned as a key component for the success of the IRS. Participants should meet with their mentor(s) quarterly, at minimum, to ensure that milestones of the research plan are met.
  • Scientific Director (SD) must approve the choice of mentors in advance.
  • IC-managed evaluation of participants’ progress every 18 months. ICs have the option of convening a review committee of IC senior staff supplemented with subject matter experts, or using their BSC to handle the review. Report to be submitted to OIR.
  • Central long-term tracking to follow future of candidates and evaluate program success.

Application Process

Note: The program is not currently accepting applications.

First Established: Tuesday, August 21, 2018

This page was last updated on Wednesday, January 22, 2025

Main navigation

  • Board of Scientific and Clinical Directors
    • Board of Scientific and Clinical Directors Membership
    • NIH IRP Scientific Directors
    • NIH IRP Clinical Directors
    • Board of Scientific and Clinical Directors Subcommittees
  • Committees Advisory to the DDIR
    • Assembly of Scientists (AOS)
    • Committee on Scientific Conduct and Ethics (CSCE)
    • Central Tenure Committee (CTC)
    • Chairs of the Boards of Scientific Counselors
    • Tenure-Track Investigators Committee
    • Women Scientist Advisors (WSA) Committee
    • Animal Research Advisory Committee (ARAC)
    • Dual Use Research of Concern (DURC) Committee
    • Facilities Working Group
    • NIH Space Recommendation Board
    • PHS Technology Transfer Policy Board
  • Processes for Reviewing NIH Intramural Science
    • Boards of Scientific Counselors (BSC)
      • Process for Appeal to a BSC Review
    • Role and Review of Scientific Directors and Clinical Directors
    • Blue Ribbon Panel Reviews of IC Intramural Research Programs
  • Intramural Program Oversight
    • Electronic Lab Notebooks
      • Intramural Electronic Lab Notebook Policy
      • Frequently Asked Questions About the Use of ELNs at NIH
    • Human Subjects Research
    • Intramural Data Sharing
      • 2023 NIH Data Management and Sharing Policy
      • Genomic Data Sharing
      • Human Data Sharing
      • Guide to FDAAA Reporting Research Results
        • Frequently Asked Questions: NIH Clinical Trial Definition
        • Assistance Available to Help with Results Reporting to ClinicalTrials.gov
          • Points of Contact for FDAAA Compliance at ICs
    • IRP Research Security
    • Laboratory Safety
    • Management Controls Survey
  • Intramural Administrative Management Council
    • List of Council Members
    • List of Trans-NIH Committees
  • Personnel
    • IPDs and Appointment Mechanisms
      • Official List of Approved Intramural Professional Designations (IPDs)
      • Senior Investigator
      • Investigator
      • Senior Clinician
      • Senior Scientist
      • Assistant Clinical Investigator
      • Staff Clinician
      • Staff Scientist
        • Explanation of Staff Scientist Position and Titles to Academic Colleagues
      • Senior Research Assistant / Research Assistant
      • Adjunct Investigator
      • Scientist Emeritus
      • Intramural Research Training Award (IRTA) Fellow
      • Visiting Fellow
      • ORISE Senior Fellow
      • Senior Clinical Fellow
      • Clinical Fellow
      • Senior Research Fellow
      • Research Fellow
        • Independent Research Scholar Program
      • Student Opportunities
      • Contractors
      • Guest Researchers / Special Volunteers
      • Research Collaborators
    • Faculty Development
      • 2024 OITE/OIR Professional Development Curriculum for NIH Faculty
      • Senior Advisors for Faculty Development
    • Policies and Recruitment Processes
      • 5-Year / 8-Year Duration Rule
      • Addendum to On-Site Research Collaborators (RC) Policies: On-Site RC Conducting Human Subjects Research at NIH
      • Clarification on Searches for Scientific Director and Clinical Director
      • Departing Staff Request to Remove Copies of NIH Records
      • Extension Exceptions for Non-FTE Trainees for COVID-19
      • Fair Review Principles for Nominations of Staff Scientists for Associate Scientist and Senior Associate Scientist Titles
      • Guide for Avoiding Undue Foreign Interference with IRP Research
      • Guidelines for Parental/Family Excused Absence for IRTAs, CRTAs, and Visiting Fellows
      • Mandated Training for Scientific Staff Working in NIH Facilities
      • Policy for a Letter of Agreement for Staff Scientists
      • Policy for Reassignment or Early Termination of Awards to Postbaccalaureate Fellows
      • Policy for Reassignment or Early Termination of Awards to Postdoctoral Fellows
      • Policy for Reassignment or Early Termination of Awards to Predoctoral Fellows
      • Policy for Use of Contract Workers to Support Scientific Functions in the IRP
      • Policy on Use of English for Official Scientific Communication in NIH Laboratories and Branches
      • Postdoctoral Fellows (IRTA/CRTA/VF) Temporary Exceptional Extensions Policy
      • Roles of Lab and Branch Chiefs (or Equivalent)
      • Telework Policies for IRTA/CRTA and Visiting Fellows
      • Working with Displaced Title 42 Staff Scientists/Clinicians
    • Quality-of-Life Features
    • Sabbaticals
      • NIAAA Sabbatical Program
      • NEI Sabbatical Program
      • NICHD Sabbatical Program
      • PHS Foreign Work / Study Program Policy
    • Opportunities for Short Assignments / Details at the NIH
  • Tenure in the NIH Intramural Research Program
    • Tenure-Track Overview
    • Search & Selection
      • Search Process for Senior Investigators, Tenure-Track Investigators, Senior Clinicians and Senior Scientists
    • Additional Tenure-Track Policies
    • Resources
    • Policy on IC Tenure Review Committees
    • Tenure Overview
    • Search & Selection
    • Criteria for Tenure at the NIH
    • De-Tenuring Process
  • Awards, Fellowships, & Grant Opportunities
    • The Director’s Challenge Innovation Award Program
      • 2020 Director’s Challenge Awards
      • 2022 Director’s Challenge Awards
      • 2024 Director’s Challenge Awards
    • Early Career (Bridge) Awards Open to IRP Scientists
    • Eligibility of Intramural Investigators for NIH Common Fund Awards
    • K99/R00 Grant Award Information
      • Application Approval Process and Additional Information
      • K99/R00 Environment and Institutional Commitment Statement
      • Update from Scientific Directors
    • NIAID Support of Intramural Biodefense Research from ICs Other Than NIAID
  • Ethical Conduct
    • Research Misconduct
      • Anonymous Reporting of Research Misconduct Concerns
      • Taraswi Banerjee, Ph.D.
      • Alfredo R Sancho, Ph.D., M.P.H.
    • Guidelines on Conduct of Research
    • Research Ethics
      • NIH Policies
        • Intramural / Extramural Collaborations
          • NIH Staff Involvement on Extramural Awards - Cooperative Agreements
            • Opportunities for Collaborative Research at the Clinical Center (U01)
            • NIH Bench-to-Bedside Program
          • Activities with Outside Organizations
        • NIH Human Biospecimen Program
          • Frequently Asked Questions
          • List of Biospecimen Liaisons
        • Investigation of Allegations of Research Misconduct
      • NIH Guidelines
    • Authorship Guidelines and Resources
      • Authorship Resources
      • NIH IRP Authorship Conflict Resolution Process
    • Special Research Considerations
      • Dual-Use Research
      • Policy on the Ordering or Provision of Synthetic Nucleic Acids in the IRP
      • Human Stem Cell Use
        • Human Embryonic Stem Cell (hESCs) Use
        • Induced Pluripotent Stem Cells (iPSCs) Use
        • Human Embryo Research and Cloning Prohibitions
      • Policies & Procedures for Human Fetal Tissue Research
    • Responsible Conduct of Research Training
      • Instruction in Responsible Conduct of Research - Postdoc IRTA, CRTA, VF, Research Associates
        • Reproducibility Training
        • Introduction to “My Laboratory”
      • Instruction in Responsible Conduct of Research - Postbacs and GPP Students
      • Resources for Training Directors
      • Annual Review of Ethics (Case Studies)
        • Research Cases for Use by the NIH Community
          • 2021 Ethics Case Facilitator Training
    • Government Ethics
      • Guidelines for Non-FTEs (Trainees) for NIH-Related Activities, Outside Activities, and Awards
    • Bioethics
  • Mentoring & Training
    • Guide to Training and Mentoring
    • Guidelines for Mentors at NIH
    • Guidelines for Trainees at NIH
    • Guidelines for Annual Progress Review of Trainees
    • Scientific Director Policy Updates for Mentors and Trainees
    • Goals for Enhanced Mentoring in the IRP
    • FelCom Mentoring Committee
    • Mentoring Cases for Discussions
  • Submitting Research Publications
    • PubMed Central (PMC) Deposition Requirements
    • Intramural Directions for Submitting to PubMed Central via NIHMS
    • NIH Publishing Agreement Forms
      • Procedures for Non-Peer-Reviewed Publications
    • Publication and Abstract Clearance
  • Intramural Research Communications & Resources
    • Annual Reports and Bibliographies
  • Email
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Main navigation

  • About OIR
    • OIR Leadership & Staff
    • DDIR Innovation Awards
    • Long-Term IRP Planning
    • OIR Offices
  • Sourcebook
    • Board of Scientific and Clinical Directors
    • Committees Advisory to the DDIR
    • Processes for Reviewing NIH Intramural Science
    • Intramural Program Oversight
    • Intramural Administrative Management Council
    • Personnel
    • Tenure in the NIH Intramural Research Program
    • Awards, Fellowships, & Grant Opportunities
    • Ethical Conduct
    • Mentoring & Training
    • Submitting Research Publications
    • Intramural Research Communications & Resources
  • Lectures & Events
    • WALS
    • NIH Research Festival
  • SIGs
    • SIGs by Name
    • SIGs by Scientific Focus Area
  • IRP Website
    • A premier environment where creative scientists conduct fundamental research for the betterment of human health – we are the IRP
    • Visit Website
  • The NIH Catalyst
    • A publication for and about the NIH intramural research community
    • Visit Website
  • NIDB
    • The NIH Intramural Database collects and disseminates information about research being performed in the Intramural Programs
    • Visit Website
  • Department of Health and Human Services
  • National Institutes of Health
  • USA.gov

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