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NIAID Support of Intramural Biodefense Research from ICs Other Than NIAID

The NIAID will make approximately $10million available for intramural researchers from ICs other than NIAID who propose highly meritorious research relevant to the NIAID Research Agenda for CDC Category A Agents. This document describes the scope of the NIH intramural initiative, and the process by which interested investigators may be funded.

Background

For the purposes of the NIAID strategic plan for biodefense research, and the specific research agenda that follows from it, bioterrorism is defined as the intentional use of microorganisms that cause human disease, or of toxins derived from them, to harm individual people or to elicit widespread fear or intimidation of society. Bioterrorism is a subset of the larger problem of emerging infectious diseases. The NIAID program for Biodefense Research is built on this concept. It is directed primarily toward the needs of civilian populations (although interventions emerging from it may have application in military settings). Research addressing terrorism resulting from the use of chemical toxins, nuclear energy, or organisms/toxins primarily affecting other animals or plants is the primary responsibility of other U.S. government agencies. The NIAID may collaborate with those agencies and organizations on such research when there is mutual opportunity for scientific or public health gain, and overlap in scientific mission.

NIAID’s Strategic Plan

The NIAID will address the challenges of bioterrorism and emerging infectious diseases through a program of basic and translational research aimed at ensuring and improving the public health and preparedness against terrorist attack of civilian populations. The institute’s Strategic Plan and Research Agenda for CDC Category A Agents emphasizes: 1) basic research on microbes and host defenses; and 2) targeted, milestone-driven development of drugs, vaccines, other interventions, and diagnostics. The plan will be executed through traditional and novel programs of support, in collaboration with partners in academia, industry, and other private and public sector agencies.

Elements of the Program

  • NIAID will make available up to $10 million annually (contingent on Congressional approval of the President’s budget request), beginning in FY03, for support of meritorious basic or applied research projects that are proposed and carried out by intramural NIH or FDA investigators from ICs other than NIAID.
  • The research must be directly responsive to the Counter-Bioterrorism Research Agenda of the NIAID for CDC Category A Agents.
  • Projects may be laboratory or clinical in nature. Clinical intervention projects should, in general, be preliminary or exploratory in nature; large clinical trials will not be supported by this mechanism.
  • The proposed research must be consistent with the investigator’s expertise and the scientific focus of his/her laboratory.
  • Support may include costs for equipment, supplies, and non-permanent personnel needed to carry out the project.
  • The investigator’s IC must provide the space and other infrastructure, as well as support for any renovation or construction required for the project.
  • Projects may be funded for periods of up to 3 years, at a total cost of $500,000 (over the 3 year period). Continued funding beyond the original period will be contingent upon satisfactory review of progress and plans.
  • Funded investigators will participate in an annual one-day meeting that will include a presentation of the progress of each funded project.
  • NIAID intramural researchers may be included as un-funded collaborators on projects.

Proposal Submission, Review, and Funding

  • Investigator prepares and submits a brief proposal (5 page maximum, including budget) to his/her Scientific Director.
    1. Title
    2. Abstract
    3. Research Proposal
    4. Statement of relevance to the NIAID Research Agenda
    5. Proposed Budget
    6. A 2 page (max) APPENDIX addressing the review criterion "Expertise and qualifications of investigator team" should document the PI’s relevant expertise, and the relevance of the proposed research to the scientific focus of his/her laboratory. Either the standard PHS autobiographical sketch or an abbreviated CV is acceptable as long as it provides sufficient information.
  • Scientific Director approves the proposal and forwards to NIAID, Assistant Director for Biodefense Research

Proposal Due Date: August, 2002

  • Proposal is screened for relevance to NIAID Research Agenda
  • Proposal undergoes peer review for scientific merit by a relevant committee of intramural scientists (NIAID and other ICs), using the following criteria:
    1. Relevance to the NIAID Research Agenda for CDC Category A Organisms
    2. Merit of the proposed research
    3. Expertise and qualifications of investigator team
    4. Reasonableness of budget
  • Peer review committee assigns level of enthusiasm and makes budget recommendations
  • Funding decision will be made by NIAID
  • Funding will be by interagency transfers of annual increments for the period of funding

Additional Information Contact

Jack Killen, M.D.
NIAID Asst. Director for Biodefense Research
Building 31, Room 7A28
Bethesda, M.D. 20892
Telephone: 301-451-4262
Fax: 301-480-1593
E-mail Address: jkillen@nih.gov

This page was last updated on Tuesday, August 10, 2021

Main navigation

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      • Genomic Data Sharing
      • Human Data Sharing
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          • Points of Contact for FDAAA Compliance at ICs
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      • Clarification on Searches for Scientific Director and Clinical Director
      • Departing Staff Request to Remove Copies of NIH Records
      • Extension Exceptions for Non-FTE Trainees for COVID-19
      • Fair Review Principles for Nominations of Staff Scientists for Associate Scientist and Senior Associate Scientist Titles
      • Guide for Avoiding Undue Foreign Interference with IRP Research
      • Guidelines for Parental/Family Excused Absence for IRTAs, CRTAs, and Visiting Fellows
      • Mandated Training for Scientific Staff Working in NIH Facilities
      • Policy for a Letter of Agreement for Staff Scientists
      • Policy for Reassignment or Early Termination of Awards to Postbaccalaureate Fellows
      • Policy for Reassignment or Early Termination of Awards to Postdoctoral Fellows
      • Policy for Reassignment or Early Termination of Awards to Predoctoral Fellows
      • Policy for Use of Contract Workers to Support Scientific Functions in the IRP
      • Policy on Use of English for Official Scientific Communication in NIH Laboratories and Branches
      • Postdoctoral Fellows (IRTA/CRTA/VF) Temporary Exceptional Extensions Policy
      • Roles of Lab and Branch Chiefs (or Equivalent)
      • Telework Policies for IRTA/CRTA and Visiting Fellows
      • Working with Displaced Title 42 Staff Scientists/Clinicians
    • Quality-of-Life Features
    • Sabbaticals
      • NIAAA Sabbatical Program
      • NEI Sabbatical Program
      • NICHD Sabbatical Program
      • PHS Foreign Work / Study Program Policy
    • Opportunities for Short Assignments / Details at the NIH
  • Tenure in the NIH Intramural Research Program
    • Tenure-Track Overview
    • Search & Selection
      • Search Process for Senior Investigators, Tenure-Track Investigators, Senior Clinicians and Senior Scientists
    • Additional Tenure-Track Policies
    • Resources
    • Policy on IC Tenure Review Committees
    • Tenure Overview
    • Search & Selection
    • Criteria for Tenure at the NIH
    • De-Tenuring Process
  • Awards, Fellowships, & Grant Opportunities
    • The Director’s Challenge Innovation Award Program
      • 2020 Director’s Challenge Awards
      • 2022 Director’s Challenge Awards
      • 2024 Director’s Challenge Awards
    • Early Career (Bridge) Awards Open to IRP Scientists
    • Eligibility of Intramural Investigators for NIH Common Fund Awards
    • K99/R00 Grant Award Information
      • Application Approval Process and Additional Information
      • K99/R00 Environment and Institutional Commitment Statement
      • Update from Scientific Directors
    • NIAID Support of Intramural Biodefense Research from ICs Other Than NIAID
  • Ethical Conduct
    • Research Misconduct
      • Anonymous Reporting of Research Misconduct Concerns
      • Taraswi Banerjee, Ph.D.
      • Alfredo R Sancho, Ph.D., M.P.H.
    • Guidelines on Conduct of Research
    • Research Ethics
      • NIH Policies
        • Intramural / Extramural Collaborations
          • NIH Staff Involvement on Extramural Awards - Cooperative Agreements
            • Opportunities for Collaborative Research at the Clinical Center (U01)
            • NIH Bench-to-Bedside Program
          • Activities with Outside Organizations
        • NIH Human Biospecimen Program
          • Frequently Asked Questions
          • List of Biospecimen Liaisons
        • Investigation of Allegations of Research Misconduct
      • NIH Guidelines
    • Authorship Guidelines and Resources
      • Authorship Resources
      • NIH IRP Authorship Conflict Resolution Process
    • Special Research Considerations
      • Dual-Use Research
      • Policy on the Ordering or Provision of Synthetic Nucleic Acids in the IRP
      • Human Stem Cell Use
        • Human Embryonic Stem Cell (hESCs) Use
        • Induced Pluripotent Stem Cells (iPSCs) Use
        • Human Embryo Research and Cloning Prohibitions
      • Policies & Procedures for Human Fetal Tissue Research
    • Responsible Conduct of Research Training
      • Instruction in Responsible Conduct of Research - Postdoc IRTA, CRTA, VF, Research Associates
        • Reproducibility Training
        • Introduction to “My Laboratory”
      • Instruction in Responsible Conduct of Research - Postbacs and GPP Students
      • Resources for Training Directors
      • Annual Review of Ethics (Case Studies)
        • Research Cases for Use by the NIH Community
          • 2021 Ethics Case Facilitator Training
    • Government Ethics
      • Guidelines for Non-FTEs (Trainees) for NIH-Related Activities, Outside Activities, and Awards
    • Bioethics
  • Mentoring & Training
    • Guide to Training and Mentoring
    • Guidelines for Mentors at NIH
    • Guidelines for Trainees at NIH
    • Guidelines for Annual Progress Review of Trainees
    • Scientific Director Policy Updates for Mentors and Trainees
    • Goals for Enhanced Mentoring in the IRP
    • FelCom Mentoring Committee
    • Mentoring Cases for Discussions
  • Submitting Research Publications
    • PubMed Central (PMC) Deposition Requirements
    • Intramural Directions for Submitting to PubMed Central via NIHMS
    • NIH Publishing Agreement Forms
      • Procedures for Non-Peer-Reviewed Publications
    • Publication and Abstract Clearance
  • Intramural Research Communications & Resources
    • Annual Reports and Bibliographies
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    • Long-Term IRP Planning
    • OIR Offices
  • Sourcebook
    • Board of Scientific and Clinical Directors
    • Committees Advisory to the DDIR
    • Processes for Reviewing NIH Intramural Science
    • Intramural Program Oversight
    • Intramural Administrative Management Council
    • Personnel
    • Tenure in the NIH Intramural Research Program
    • Awards, Fellowships, & Grant Opportunities
    • Ethical Conduct
    • Mentoring & Training
    • Submitting Research Publications
    • Intramural Research Communications & Resources
  • Lectures & Events
    • WALS
    • NIH Research Festival
  • SIGs
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    • SIGs by Scientific Focus Area
  • IRP Website
    • A premier environment where creative scientists conduct fundamental research for the betterment of human health – we are the IRP
    • Visit Website
  • The NIH Catalyst
    • A publication for and about the NIH intramural research community
    • Visit Website
  • NIDB
    • The NIH Intramural Database collects and disseminates information about research being performed in the Intramural Programs
    • Visit Website
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