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NIH Director’s Wednesday Afternoon Lecture Series

Upcoming Lectures

The VHL tumor suppressor: insights into oxygen sensing, cancer metabolism, and drugging the undruggable

January 24, 2018 - 3:00pm to 4:00pm
William G. Kaelin Jr., M.D., Dana-Farber Cancer Institute, Harvard Medical School

A Howard Hughes Medical Investigator since 1998, Dr. Kaelin's research seeks to understand how, mechanistically, mutations affecting tumor-suppressor genes cause cancer. His long-term goal is to lay the foundation for new anticancer therapies based on the biochemical functions of tumor suppressor proteins. His work on the VHL protein helped to motivate the eventual successful clinical testing of VEGF inhibitors for the treatment of kidney cancer.

The molecular logic of synapse formation in the brain

January 31, 2018 - 3:00pm to 4:00pm
Thomas Christian Südhof, M.D., Stanford School of Medicine

Thomas Südhof is interested in how synapses form and function in the developing and adult brain. His work focuses on the role of synaptic cell-adhesion molecules in establishing synapses and shaping their properties, on pre- and postsynaptic mechanisms of membrane traffic, and on impairments in synapse formation and synaptic function in neuropsychiatric and neurodegenerative disorders.

Sugar and the beating heart - the conundrum of heart failure in diabetes

February 7, 2018 - 3:00pm to 4:00pm
E. Dale Abel, M.D., Ph.D. , University of Iowa

Dr. Abel's current research interests focus on elucidating the molecular mechanisms leading to cardiac dysfunction in diabetes and the regulation of myocardial growth and metabolism by insulin signaling.


The page was last updated on Monday, March 23, 2015 - 3:00pm