Dr. Trevor Bedford uses powerful computers and complex statistical methods to study the rapid spread and evolution of viruses, including those that cause COVID-19, influenza, Ebola and Zika. Data gathered from these processes help researchers develop successful strategies for monitoring and controlling infectious diseases. His visual representations of viral family trees are used to show how the fate of dangerous outbreaks is often determined by the genetics of the infectious agent, human behavior and geography. Dr.
Dr. Susan Parkhurst studies the cytoskeleton, the cell’s internal framework. The cytoskeleton is a dynamic structure, constantly forming and breaking down to meet the cell’s changing needs, including changes in shape and movement. Problems with building and deconstructing the cytoskeleton arise in many human diseases. Wound healing, in which cells move to fill a gap, and the organization of the nucleus, the cell’s DNA storeroom, rely on the cytoskeleton. Dr. Parkhurst studies its roles in these normal conditions and what goes wrong in cancer cells.
Our work encompasses the following areas: the development of methods for the detection of and protection against chemical/biological warfare agents, the preparation of combinatorial chemical libraries, the design/synthesis and evaluation of catalytic antibodies and enzyme inhibitors, solid-phase organic synthesis, antibody/peptide phage display libraries, the application of immunopharmacotherapy in the treatment of drug addiction and cancer, methods of prevention and treatment of obesity, diagnostic and therapeutic strategies towards neglected tropical diseases, and investigation and develo
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