NIH Director’s Wednesday Afternoon Lecture Series
The information for this lecture has not yet been made available. Please check back soon for an updated overview.
Lack of inclusion of under represented populations in biomedical research contribute to inequities in health. The NIH Precision Medicine Initiative intends to build bridges from genome medicine to data science by reaching over 1 million Americans. It is not certain that under represented populations will actively engage PMI and other NIH discovery science opportunities. This persistent lack of participation will likely exacerbate health disparities even in this new age of genome science and digital technology.
Elements of health and disease: inorganic fluxes and metal receptors that control cell fate decisions
For the past three decades, Thomas V. O’Halloran has investigated how fluctuations in the amount of metal ions inside cells influence key cellular decisions. Using genetic, chemical, structural and mechanistic approaches, he has uncovered new types of metal receptors and tied their function to a number of disease-related physiological processes. O’Halloran identified early examples of metal ion receptors called metalloregulatory proteins that regulate gene expression.
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