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Epigenetics Interest Group

Epigenetics represents a new frontier in cancer research. Information in the genome exists in at least two forms, genetic and epigenetic. The genetic information provides the blue print for the manufacture of all the proteins necessary to create a living organism, whereas the epigenetic information provides additional instructions on how, where, and when the genetic information will be used. The focus of the Epigenetics Interest Group is on applications of epigenetic approaches in disease detection, risk assessment and treatment. The group meets on last Thursday of every month from 3-4 pm. Please contact Dr. Mukesh Verma at 240-276-6889 for more information.

Colleagues interested in epigenetics may benefit from a course offered by the Foundation for Advanced Education in the Sciences (FAES) at NIH:

BIOC532, Chromatin modifications and their biological importance
Term and Year: 2020 – Spring
Time: Tuesday: 5:30-7:30 pm
Class Room: Building 5, Conference Room 127

Course Description: The Bioc532 course will explore the various biological roles chromatin modifications play in eukaryotic cells. Topics that will be discussed include: histone and DNA modifications and the enzymes responsible for these modifications; mechanisms of chromatin remodeling and transcription regulation; the role of DNA methylation and non-coding RNAs in chromatin structure and gene regulation; Chromatin modifications and DNA repair; higher-order chromatin organization and the research tools (3C, 4C, HiC methods). In addition, this course will introduce students to the genome-wide analysis of ChIP-seq, RNA-seq and HiC data using a variety of computer software, including using the public accessible web servers, such as UCSC genome browser. 

For more information about the course, please contact Instructor: Tiaojiang Xiao, xiaotiao@mail.nih.gov; phone number: 301-451-8157.


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The page was last updated on Thursday, December 5, 2019 - 4:36pm