A daily period of unproductivity: Can we solve the mystery of sleep?
Amita Sehgal, Ph.D.
John Herr Musser Professor
University of Pennsylvania Perelman School of Medicine
The overall goal of the Sehgal lab is to determine the mechanisms that drive circadian rhythms and sleep, and to address the importance of these processes for organismal fitness. Most physiological processes display circadian (~24h) rhythms driven by endogenous clocks. Dr. Sehgal’s interest is in sleep in particular, which, in addition to the clock, is controlled by a homeostatic system that ensures adequate sleep for an organism. Most of our work is conducted with Drosophila, although we also use mammalian models. We are addressing the daily timing of sleep, the molecular and circuit mechanisms that drive sleep, and also the consequences of lost or disrupted sleep.
This page was last updated on Wednesday, August 11, 2021