From microbial immunity to genome editing
Feng Zhang, Ph.D.
Core Member, The Broad Institute of MIT
Investigator, McGovern Institute for Brain Research
Associate Professor, Departments of Brain and Cognitive Sciences and Biological Engineering
Massachusetts Institute of Technology
Our research focuses on the development and application of novel molecular technologies for studying the nervous system. Given the complexity of the brain, it is important to develop both precise perturbation as well as quantitative readout methodologies so that we can systematically reverse-engineer how the brain is functionally organized. So far my work has focused on the development of optogenetics technologies for controlling neural activity with high temporal, spatial, and cell-type specificity; and, more recently, genome engineering technologies based on CRISPR-Cas systems to allow precise alteration or modulation of the mammalian genome to unravel genetic and molecular mechanisms underlying nervous system function and disease.
This page was last updated on Wednesday, August 11, 2021