Colliding Ribosomes Function as a Sentinel for Cellular Distress
Rachel Green began her scientific career majoring in chemistry as an undergraduate at the University of Michigan. Her doctoral work was performed at Harvard in the laboratory of Jack Szostak where she studied RNA enzymes and developed methodologies for evolving RNAs in vitro. She came to the JHU School of Medicine in 1998 following post-doctoral work in Harry Noller’s lab at UC Santa Cruz where she began her work on ribosomes. Her laboratory is interested in deciphering the molecular mechanisms that are at the heart of protein synthesis and its regulation across biology. This focus allows her to still think about the earliest evolutionary steps that led to life on earth, but in a system where biological questions drive the experiments. Her laboratory uses both biochemical and genomic approaches to get at these questions in bacterial and eukaryotic system.
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