Skip to main content
 

RESCHEDULED for DEC. 9 – Casting the Net Wide: the Role of Neutrophils in Chronic Diseases

Wednesday, April 29, 2020 - 3:00pm to 4:00pm

Speaker

Mariana J. Kaplan, M.D.
Senior Investigator
Chief, Systemic Autoimmunity Branch
Deputy Scientific Director
National Institute of Arthritis and Musculoskeletal and Skin Diseases

In support of the Office of Personal Management guidance to strengthen efforts to protect the federal workforce and to ensure continuity of operations during the COVID-19 outbreak, the NIH Director is requesting that NIH-sponsored large meetings and symposia scheduled for March and April be held virtually, postponed, or cancelled.

Summary

Dr. Kaplan's lecture has been rescheduled to December 9, 2020. 

Dr. Kaplan's research has focused on identifying mechanisms of immune dysregulation, organ damage and premature vascular disease in systemic autoimmunity. More specifically, she investigates how innate immunity (in particular, type I interferons and myeloid cells) promote end-organ damage in systemic lupus erythematosus, rheumatoid arthritis and other systemic autoimmune diseases. Recently, her research has focused on identifying abnormalities of neutrophil subsets and the role of neutrophil extracellular traps (NETs) in lupus and rheumatoid arthritis, both of which may contribute to the development of autoimmune responses and to end-organ damage. Dr. Kaplan also has an interest in identifying novel therapeutic targets that may prevent premature vascular damage in systemic autoimmunity, as well as the role of environmental triggers in the induction of autoimmunity. Moreover, she has led clinical trials to identify mechanisms that reduce blood vessel dysfunction in autoimmune and chronic inflammatory disorders.


The page was last updated on Thursday, April 9, 2020 - 3:55pm