Skip to main content

Special Lecture

The two faces of the IL-15- Janus Kinase-Stat system: implications for the immunotherapy of autoimmune diseases and cancer

November 29, 2017 - 3:00pm to 4:00pm
Thomas A. Waldmann, M.D., National Cancer Institute

Dr. Walmann will present the annual William Paul lecture. Dr. Waldmann defined the IL-2 receptor alpha and beta subunits using the daclizumab antibody he discovered, an antibody that is approved by the FDA. He co-discovered IL-15 and performed the first in-human clinical trial with this agent in patients with malignancy. Furthermore, Waldmann defined molecular abnormalities of the common gamma cytokine, Jak/Stat signaling pathway in HTLV-1 associated adult T-cell lymphoma and translated this discovery with a trial of a Jak inhibitor in patients with this disorder.

Systems science and innovation in health care delivery

June 13, 2017 - 2:00pm to 3:00pm
Atul Gawande, M.D., M.P.H., Harvard T.H. Chan School of Public Health

Dr. Gawande is a surgeon, writer, and public health researcher. He practices general and endocrine surgery at Brigham and Women’s Hospital in Boston, Massachusetts. He is Professor in the Department of Health Policy and Management at the Harvard T.H. Chan School of Public Health and the Samuel O. Thier Professor of Surgery at Harvard Medical School. He is also Executive Director of Ariadne Labs, a joint center for health systems innovation, and Chairman of Lifebox, a nonprofit organization making surgery safer globally. Dr.

Stressed out: a novel approach to cancer immunotherapy

November 7, 2016 - 3:00pm to 4:00pm
Laurie Glimcher, M.D. , Dana-Farber Cancer Institute

Dr. Glimcher is President and CEO of Dana-Farber Cancer Institute, Principal Investigator and Director of Dana-Farber/Harvard Cancer Center and the proposed Richard and Susan Smith Professor of Medicine at Harvard Medical School. Previously, she was the Stephen and Suzanne Weiss Dean and Professor of Medicine of Weill Cornell Medical College in New York City, and Provost for Medical Affairs of Cornell University. Prior to her work at Cornell, Dr.

Neuromodulatory circuits and motivated behavior

September 9, 2013
Cori Bargmann, Ph.D., The Rockefeller University

Genetic variation, internal states, and environmental cues converge on shared neuronal circuits to regulate behaviors. In the nematode worm Caenorhabditis elegans, an anatomical wiring diagram provides an essential map for innate behaviors, such as preferences for specific stimuli. Superimposed on this detailed circuit diagram are neuromodulators reflecting internal states, which help select appropriate behavioral responses from a larger number of latent circuits, and lead to both rapid and long-lasting changes in behavior. Dr.

The page was last updated on Thursday, January 29, 2015 - 2:25pm