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Current Lecture Season

Microbiome: friend and foe

April 3, 2019 - 3:00pm to 4:00pm
Julie Segre, Ph.D., National Human Genome Research Institute

Dr. Segre’s research at NHGRI explores human skin bacterial, fungal and viral communities, enabling studies of alterations associated with pediatric atopic dermatitis, primary immunodeficiency and emerging pathogens. Dr. Segre’s research also focuses on integrating whole genome sequencing of hospital pathogens to track possible nosocomial transmissions. These studies integrate DNA sequence technology, algorithm development and clinical studies to explore the diversity of microbes in and on humans in health and disease.

RNA degradation controls inflammation

April 10, 2019 - 3:00pm to 4:00pm
Shizuo Akira, M.D., Ph.D., Osaka University

Dr. Akira is a director and special appointed professor of Immunology Frontier Research Center. He received his M.D. and Ph.D. from Osaka University. After two years of postdoctoral working in Department of Immunology, University of California at Berkeley, he started to study on IL-6 gene regulation and signaling in the Institute for Molecular and Cellular Biology, Osaka University, and cloned transcription factors, NF-IL6(C/EBP beta) and STAT3.

The secret lives of cells

April 24, 2019 - 3:00pm to 4:00pm
Eric Betzig, Ph.D., University of California, Berkeley

From the 17th through the 19th century, beautifully artistic micrographs of living specimens were inextricably linked to biological discovery. However, for much of the 20th century, optical microscopy took a back seat to the powerful new fields of genetics and biochemistry. Starting in the 1980s, the tables started to turn again, thanks to the widespread availability of computers, lasers, sensitive detectors, and fluorescence labeling techniques.

The biosynthesis of lipoic acid: a saga of death, destruction, and rebirth

May 1, 2019 - 3:00pm to 4:00pm
Squire J. Booker, Ph.D. , The Pennsylvania State University

Research in the Booker Lab focuses on understanding how Nature harnesses the power of radicals to effect kinetically challenging enzymatic reactions, many of which are critical to proper cellular functioning. Much of the lab’s work has centered around the enzymatic use of S-adenosylmethionine and iron-sulfur clusters to generate a 5’-deoxyadenosyl 5’-radical, used as a key intermediate by members of the radical S-adenosylmethionine (SAM) superfamily to catalyze over 60 different reaction types.

Getting by with a little help from their friends: how bacteria aid virus infection

May 8, 2019 - 3:00pm to 4:00pm
Julie Pfeiffer, Ph.D. , UT Southwestern Medical Center

Dr. Pfeiffer studies RNA virus evolution, dissemination, pathogenesis, and transmission. Her recent interests include examining the impact of intestinal microbiota on enteric virus infections. Her lab has determined that intestinal bacteria promote replication of several enteric viruses and ongoing work is examining mechanisms and consequences of bacteria-virus interactions. 

A community approach to breast cancer prevention: addressing health disparities

May 15, 2019 - 3:00pm to 4:00pm
Lucile Adams-Campbell, Ph.D., Georgetown University

Dr. Adams-Campbell's areas of research focus on addressing health disparities with particular emphasis on cancers that disproportionately impact African-Americans. Dr. Adams-Campbell's research focuses on lifestyle interventions including physical activity, energy balance, obesity, metabolic syndrome, and oral health among minority and underserved populations.

Genes, lifestyle, and risk for heart attack

May 22, 2019 - 3:00pm to 4:00pm
Sekar Kathiresan, M.D. , Harvard Medical School

Dr. Kathiresan leverages human genetics to understand the root causes of heart attack and to improve preventive cardiac care. Among his scientific contributions, Dr. Kathiresan has helped highlight new biological mechanisms underlying heart attack, discovered mutations that protect against heart attack risk, and developed a genetic test for personalized heart attack prevention.

Opiates on the brain

May 29, 2019 - 3:00pm to 4:00pm
Brigitte Kieffer, Ph.D. , Douglas Hospital Research Center

Dr. Kieffer is a basic scientist and neurobiologist. She isolated the first gene encoding an opioid receptor, a landmark in neuroscience research to understanding molecular bases of opioid transmission and opioid-mediated mechanisms underlying pain control, mood disorders and addiction. Her team elucidated the role of each opioid receptor in both known and unknown areas of opioid physiology and behaviors using gene knockout in mice. She showed that mu receptors mediate both analgesic and addictive actions of morphine, and are responsible for drug and social reward.

Mitochondrial Behavior

June 5, 2019 - 3:00pm to 4:00pm
Jodi Nunnari, Ph.D. , University of California, Davis

The research in the Nunnari laboratory is devoted to understanding how the behavior of mitochondria is controlled in cells. Specifically, we are focused on two fundamental problems. The first is how the structure of mitochondria is established and maintained within cells. We are currently elucidating the molecular mechanisms that underlie mitochondrial division and fusion. Our second area of interest is on understanding how the mitochondrial genome is organized and faithfully segregated within the organelle.

Lecture Title Forthcoming

June 12, 2019 - 3:00pm to 4:00pm
Anne O'Garra, Ph.D. , The Francis Crick Institute

Dr. O'Garra studies the signals that control our immune systems, to understand how they respond to diseases such as tuberculosis and what goes wrong when they damage healthy cells.


The page was last updated on Wednesday, June 11, 2014 - 4:07pm